What is Mamofen?
Mamofen is a medicine that blocks the effects of the estrogen hormone in the body. It is used to treat breast cancer in women or men. It may also be used to treat other kinds of cancer, as determined by your doctor.
Mamofen also may be used to reduce the risk of developing breast cancer in women who have a high risk of developing breast cancer. Women at high risk for developing breast cancer are at least 35 years of age and have a combination of risk factors that make their chance of developing breast cancer 1.67% or more over the next 5 years. Your doctor will help to determine your risk of developing breast cancer.
- The following are risk factors that may increase your chance of developing breast cancer:
- If you have close family members (mother, sister, or daughter) with breast cancer.
- If you have ever had a breast biopsy or if high-risk changes in your breast(s) have been found from a breast biopsy.
- If you have never been pregnant or if your first pregnancy occurred at a late age.
- If your first menstrual period occurred at an early age.
The exact way that Mamofen works against cancer is not known, but it may be related to the way it blocks the effects of estrogen on the body.
Before you begin treatment with Mamofen, you and your doctor should talk about the good Mamofen will do as well as the risks of using it.
Mamofen is available only with your doctor's prescription.
Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, Mamofen is used in certain patients with the following medical conditions:
- Breast cancer, neoadjuvant treatment for hormone receptor-positive disease in postmenopausal women.
- Cancer of the endometrium (lining of the uterus).
- Malignant melanoma (a certain type of skin cancer).
Adjuvant treatment of breast carcinoma in women; metastatic breast carcinoma in men and women; reduction in risk of breast cancer in high-risk women; lower risk of invasive breast cancer in women with ductal carcinoma in situ (DCIS).
Ovulation stimulation in specially selected anovulatory women desiring pregnancy; management and treatment of some types of mastalgia (eg, cyclical); malignant carcinoid tumor and carcinoid syndrome; migraine associated with menstruation; metastatic malignant melanoma; oligozoospermia; McCune-Albright syndrome in female pediatric patients (in combination with other agents); metastatic melanoma; desmoid tumors; symptomatic gynecomastia.
How should I use Mamofen?
Use Mamofen as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Mamofen comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Mamofen refilled.
- Mamofen may be taken by mouth with or without food.
- Take Mamofen with water or another nonalcoholic liquid.
- Swallow this medication whole. Do not break, crush, or chew before swallowing.
- Continue to take Mamofen even if you feel well. Do not miss any doses. Taking Mamofen at the same time each day will help you to remember to take it.
- If you miss a dose of Mamofen, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Mamofen.
Uses of Mamofen in details
Mamofen is used to prevent or treat breast cancer and to treat infertility due to absence of ovulation (anovulatory infertility). It is also used to lower a woman's chance of developing breast cancer if she has a high risk (such as a family history of breast cancer).
Mamofen is an antagonist of the estrogen receptor in breast tissue. It has been the standard endocrine (anti-estrogen) therapy for hormone-positive early breast cancer, although aromatase inhibitors have been proposed for postmenopausal women.
Some breast cancer cells require estrogen to grow. Estrogen binds to and activates the estrogen receptor in these cells. Mamofen is metabolized into compounds that also bind to the estrogen receptor but do not activate it. Furthermore Mamofen prevents estrogen from binding to its receptor. Hence breast cancer cell growth is blocked.
Mamofen was discovered by ICI Pharmaceuticals (now AstraZeneca) and is sold under the trade names Nolvadex, Istubal, and Valodex. However, the drug, even before its patent expiration, was and still is widely referred to by its generic name "Mamofen."
Active ingredient matches for Mamofen:
Tamoxifen in India, Myanmar.
Tamoxifen citrate in India.
ReviewsThe results of a survey conducted on nDrugs.com for Mamofen are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Mamofen. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.
Consumer reported usefulNo survey data has been collected yet
Consumer reported price estimatesNo survey data has been collected yet
Consumer reported time for resultsNo survey data has been collected yet
Consumer reported ageNo survey data has been collected yet
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